Abstract
Bottoms and Shuster1 have shown that when hairless mouse skin is exposed to ultra-violet irradiation in vitro there is a decrease in the saline and citrate soluble collagen fractions; however, the insoluble collagen remains unchanged. At the same time, there is an increase in the toughness of the pelts. It was suggested that these effects of ultra-violet irradiation were due to increased cross-linkage between the collagen fibrils. In the experiments described here, we attempted to measure the degree of cross-linkage of mouse skin and kangaroo tail tendon collagen before and after ultra-violet irradiation.
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