Abstract

Objective To investigate the effect of ultrasound elastography (UE) combined with color Doppler flow imaging (CDFI) on the differential diagnosis of benign and malignant thyroid ultrasound imaging report and data system (TI-RADS) grade 4 lesions. Methods A total of 134 patients with thyroid TI-RADS grade 4 lesions from November 2016 to August 2018 were enrolled, including 64 patients with benign lesions and 70 patients with malignant lesions. All patients underwent UE technique and CDFI examination. The scores of UE and the characteristics of CDFI blood flow of patients with benign and malignant lesions were compared. With the pathological results as the golden standard, the values of UE technique combined with CDFI and separate examination were compared. Results (1) CDFI blood flow characteristics: Ridit test showed that the CDFI blood flow characteristics of patients with malignant lesions were significantly different from those of benign lesions (P 0.05). Conclusions The combination of UE technology and CDFI in the diagnosis of thyroid TI-RADS grade 4 lesions can significantly improve the diagnostic accuracy and sensitivity without affecting the diagnostic specificity, which can accurately identify benign and malignant lesions, judge the condition, formulate treatment plan, and provide important guidance information. Key words: Thyroid; TI-RADS grade 4; UE technology; CDFI; Benign and malignant; Diagnostic efficacy

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