Effect of triple antibiotic paste on the bond strength of epoxy and methacrylate resin-based sealers to root canal dentin.

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Purpose:This study aimed to evaluate the effect of triple antibiotic paste (TAP) as an endodontic intracanal medicament on the bond strength of epoxy and methacrylate resin-based sealers to root canal dentin.Materials and Methods:In this in vitro study, 80 single-rooted human mandibular premolars were prepared using ProTaper rotary system. The specimens were randomly divided into a control group (without intracanal dressing) and an experimental group receiving TAP (n = 40). The intracanal dressing was removed after 3 weeks. Then, samples of each group were randomly divided into four subgroups (n = 10) and obturated with gutta-percha and different resin-based sealers. G1: AH Plus, G2: Syntex, G3: EndoREZ, and G4: MetaSEAL. After 1 week, 16 slices of 1 ± 0.1 mm thickness were obtained from the midroots of teeth in each subgroup, and a push-out test was used to measure the bond strength. Slices were examined using a stereomicroscope at 30 × to determine the mode of failure. The data were analyzed using two-way analysis of variance, one-way analysis of variance, and Tukey post hoc tests (α = 0.05).Results:Compared to control group, TAP significantly increased the bond strength of MetaSEAL and EndoREZ (P < 0.05). In the control group, epoxy resin-based sealers showed higher bond strength compared to methacrylate ones (P = 0.00). In TAP group, Syntex and EndoREZ showed significantly the greatest and the lowest bond strengths, respectively, (P < 0.05). The analysis of failure modes revealed a predominance of mixed failures in all groups except for Syntex group in which most failures were cohesive.Conclusions:TAP significantly increased the bond strength of methacrylate resin-based sealers.