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https://doi.org/10.1007/bf00841060
Copy DOIPublication Date: Dec 1, 1989 |
Calcium ions are intracellular mediators of many functionally important processes. Explanation of the specific changes in calcium metabolism in transformed cells and the study of the properties of the proteins and enzymes involved in malignant change of cells are topics for investigation in modern membrane biology of tumor cells. Transport of calcium ions through the plasma membrane is the basic mechanism regulating and maintaining a low concentration of calcium ions in the cell, and is responsible for the normal course of metabolic processes [i, 3]. An important role in the regulation of work in the calciumATPase system for calcium transport through the plasma membrane is played by calmodulin [2]. It was discovered previously that active transport of calcium, coupled with increased Ca-ATPase activity, is observed in tumor cells [4].
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