Abstract
Effect of Topical Moxifloxacin on the Bacterial Flora of the Ocular Surface following Cataract Surgery: A Randomized, Single-Masked Clinical Trial
Highlights
Postoperative bacterial endophthalmitis is one of the most devastating complications following cataract surgery
Postoperative endophthalmitis is a rare condition, with reported rates ranging between 0.08% and 0.26% [1,2,3,4,5,6]; when taking into account the millions of people who have cataract surgery every year, postoperative endophthalmitis becomes a significant public health issue [7]
Sixty patients (120 eyes), regardless of age or gender, who were scheduled for cataract surgery and met the inclusion/exclusion criteria were included in the study from September 2006 to January 2007
Summary
Postoperative bacterial endophthalmitis is one of the most devastating complications following cataract surgery. In the United States, the incidence of postoperative endophthalmitis has increased from 1.79 cases per 1000 in 1994 to 2.47 cases per 1000 in 2001, an approximately 28% increase over this 7-year period [8,9]. This upward trend in endophthalmitis frequency coincides temporally with the development of sutureless clear corneal incisions, but no definitive conclusions regarding its cause can yet be made [8]. Techniques to reduce pathogens from the ocular surface include preparation of the skin and conjunctiva with povidone-iodine. It has been demonstrated that using these measures reduces pathogens from the ocular surface
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