Abstract
Methods: Non randomized controlled trial of 140 eyes was done for 12 months from Feb2007 to Jan 2008 at Department of Ophthalmology, GSVM Medical College, Kanpur. All patients coming to the outpatient department with complaints of itching, watering, redness or foreign body sensation of eyes were evaluated for inclusion in study. Patients were categorized into 2 groups: Group A: patients of Simple chronic conjunctivitis either not responding to steroids or having a recent relapse after cessation of steroids; Group B: patients of Vernal Keratoconjunctivitis. Patients were treated with topical Cyclosporine 0.05% thrice a day. Symptoms and signs were scored on the day of enrolment and then on 5th, 12th, 20th and 30th day of treatment. Conjunctival scrapings were obtained before the treatment to detect the presence of eosinophils to confirm the diagnosis of ocular allergic disease. The statistical analyses were conducted using the formula ‘Standard error of difference between two means’.
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