Abstract

Nicotine is obtained from the leaves of the Nicotiana tabacum plant, belongs to the class of parasympathomimetic alkaloids, is metabolized by the liver, and because of its dopaminergic activity, it is very addictive. Head and neck cancer risk factors include alcohol and tobacco misuse by showing synergic effects. Smokeless tobacco products have been associated with oral cancer. This article explains how the active constituent of tobacco can cause head and neck cancer, which subtype can have a greater chance of becoming cancerous in head and neck cancer, and how we can prevent using tobacco.

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