Abstract
A heteroploid cell line of human kidney cells was grown with or without the hormone 1-thyroxine. When the cells were in exponential growth the cell generation cycle characteristics were determined in control and hormone-treated populations. The life cycle of the cells was reduced from 27 to 20 h when hormone was present while the dead cell fraction remained the same. The shortening of the life cycle is due to a reduced time in the pre-DNA replication period (G1). The time to complete other stages of the life cycle appears to be virtually unchanged.
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