Abstract

Thyroid therapy in the euthyroid obstetric and gynecologic patient has been a subject of controversy for many years. On the one hand, it has been the clinical impression of gynecologists that thyroid extract has great value in the treatment of sterility and menstrual abnormalities. This view is so prevalent that one would assume there was a reasonable basis for this attitude. On the other hand, internists, medical endocrinologists, and thyroid specialists are inclined to doubt the rationale of this type of therapy and not only question its efficacy but sometimes condemn it as harmful. The purpose of this paper is to provide information that may be helpful in resolving this controversy. The relationship of thyroid disorders to menstrual abnormalities is well documented in the literature. Sehrt 1 in 1914 found that, of 30 cases of essential uterine hemorrhage, not less than 13 showed hypofunction of the thyroid gland. Kocher 2

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