Abstract
Mice aged 10 days do not produce interferon in response to injection of Newcastle disease virus (NDV). A single injection of a fraction of calf thymus extract, obtained by the method of Gyulling et al., into newborn mice conferred the ability to produce interferon on mice at the age of 10 days. In response to injection of NDV, adult rats produce interferon in high titers. The intensity of interferon synthesis was unchanged 2–3 months after thymectomy.
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