Abstract
Two Hfr strains which had recieved the thymine requiring mutation of strain 15T-, but the colicinogenic factor were isolated. Mating experiments with these Hfr's revealed that thymine starvation of Hfr cells inhibits chromosome transfer. Uracil and histidine double starvation in Hfr cells, rather than being inhibitory, protects them from the spontaneous interruption of the process. The inhibitory effect of thymine starvation is differentially active, the more distant from the origin of an Hfr chromosome a given genetic marker is located, the more strongly transfer of that marker is inhibited. This inhibitory effect is (at least, partially) reversible.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
