Abstract
When the papilloma virus is injected into the blood stream of rabbits previously tarred on the ears for 1 1/2 to 3 months, growths rapidly arise on the tarred skin, often in great numbers. Some are squamous cell carcinomas,1 usually multiple, and frequently metas-tasing.∗ We have studied the phenomenon in more than 70 rabbits, with 90 tarred controls. In none of the latter has a cancer developed.Many of the growths that follow upon injection of the virus appear where no localized proliferation was previously visible, but others derive from pre-existing tar warts, which start growing rapidly, alter in aspect, and not infrequently manifest malignancy. After tarring is stopped, most ordinary tar warts disappear and the others become indolent, whereas the virus-stimulated warts keep on enlarging. Some are now carcinomatous but may undergo conversion into characteristic virus papillomas, as a scrutiny of several hundred specimens has shown; and others have become hybrids, neither ordinary tar tumors nor ordina...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
