Abstract
Objective To investigate the effect of the number of sentinel lymph node (SLN) dissection on prediction of non-sentinel lymph node (nSLN) metastasis in SLN biopsy in patients with early-stage breast cancer. Methods A retrospective analysis of clinical and pathological data of 82 patients with early-stage breast cancer who underwent SLN biopsy and axillary lymph node dissection in the Affiliated Cancer Hospital of Shanxi Medical University from January 2015 to December 2016 was conducted, and the univariate analysis and logistic multivariate regression analysis were performed to analyze the influencing factors of nSLN metastasis. Results Univariate analysis showed that nSLN metastasis was associated with histological grade (χ2 = 10.114, P = 0.006), vascular invasion (χ2 = 12.381, P 0.05). Multivariate analysis showed that the number of positive SLN ≥ 2 was an independent influencing factor of nSLN metastasis (OR = 4.145, P = 0.015). Conclusions Surgeons need to ensure that the number of SLN dissection is > 2 when the SLN biopsy is performed in patients with breast cancer. When the number of positive SLN is ≥2, the risk of nSLN metastasis increases. Key words: Breast neoplasms; Lymph node excision; Sentinel lymph node biopsy; Non-sentinel lymph node; Neoplasm metastasis
Published Version
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