Abstract

Anaemia in patients with severe traumatic brain injury (TBI) may worsen neurologic outcome. The aim of this study was to determine the association of haemoglobin level (Hb) with neurologic outcome and to determine a transfusion threshold which may be used in future transfusion trials aimed at improving neurologic outcome in TBI patients.

Highlights

  • To assess cerebral hemodynamics in an experimental sepsis model

  • Healthy bowel function is an important factor when judging the advisability of early enteral nutrition in critically ill patients

  • Sepsis is defined as the presence of infection with systemic signs of infection, and severe sepsis as sepsis plus sepsis-induced organ dysfunction or tissue hypoperfusion [1]

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Summary

Introduction

We evaluated platelet activation markers as potential predictive markers of sepsis and of mortality among four commonly encountered populations of patients admitted to ICUs. Methods Ninety-nine non-infected ICU patients were prospectively screened at day 1 (T1) and day 3 (T2) of admission after elective cardiac surgery, trauma, acute neurologic dysfunction or prolonged ventilation (>48 hours). The present study was performed with the aim of assessing whether nursing and physician staff were able to identify patients in need of critical care using only clinical judgment and to compare this with the National Early Warning Score (NEWS) Methods This was a prospective cohort study of all adult patients with a first-time admission to a medical admission unit at a 450-bed regional teaching hospital over a 3-month period in 2010.

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