Abstract
THE FINDINGS OF Biskind and Glick (1), Ley (2), Phillips et al (3, 4), Winkler and Binder (5) and Israel and Meranze (6) during the past decade have presented evidence which is strongly suggestive of the importance of ascorbic acid in reproduction. Erb and Andrews (7), reported that the subcutaneous injection of equine gonadotropin in the male and female bovine resulted in a decrease of blood plasma-ascorbic acid of 20 to 67 per cent within 24 hours. The recovery of pre-injection ascorbic acid levels required 8 to 10 days in the cow and longer in the bull unless vitamin C was subcutaneously injected. Erb and Andrews suggested that this drop in plasma-ascorbic acid might be responsible for the frequent failure of gonadotropins to produce satisfactory gonad stimulation. Di Cio and Schteingart (8) simultaneously reported that the injection of ascorbic acid in conjunction with gonadotropin caused a greater effect on the genitalia of both the male and female rat than did the gonadotropic hormone alone.
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