Effect of the Antibiotic, Borrelidin, on the Production of L-Threonine by E. coli Auxotrophs

Abstract

The effect of an antibiotic, borrelidin, on l-threonine fermentation by E. coli auxotrophs were studied and it was found that the production of l-threonine was greatly increased by the presence of borrelidin. The production of l-threonine was considerably increased by the addition of l-aspartic acid together with borrelidin. The maximum amount of l-threonine accumulated by E. coli No. 234 was 15.0 mg/ml in the medium containing 50 mg/ml of glucose and 5 mg/ml of sodium-aspartate.