Abstract

The effects of small air ions were observed on the course of influenza in specific pathogen-free mice challenged by intranasal instillation of measured doses of influenza virus and maintained in a controlled micro-environment. Unipolar low densities of positive or negative ions increased the death rate, while mid-range densities of either charge were without effect. High concentrations of negative ions or low concentrations of mixed ions with negative ions predominating reduced the death rate. Ion depleted air, a common product of urban living conditions, significantly increased the mortality rate.

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