Abstract
The effect on rat bile composition of the essential oils from the fruits of three different chemotypes of Thapsia has been studied. For comparison, the major components of Thapsia essential oils, limonene, geranylacetate and methyleugenol, as well as menthol and peppermint oil, were also included in the investigation. Data obtained show that the tested drugs enhance bile secretion by increasing bile acid-independent flow (BAIF). Biotransformation products of the tested drugs were detected in bile samples.
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