Abstract
The solubilization of benzocaine with polyoxyethylene (23) lauryl ether and polysorbate 80 was determined as a function of temperature. The enhancement of the stability of benzocaine and homatropine solubilized with from 3 to 15% polyoxyethylene (23) lauryl ether and polysorbate 80 was quantitatively determined at 30, 50, and 70°. For the alkaline hydrolysis of benzocaine and homatropine, the logarithm of the specific rate constant is linearly related to the percent of the surface-active agent. The specific rate constant for the hydrolysis of benzocaine is linearly related to the reciprocal of the apparent solubility of benzocaine in polyoxy-ethylene (23) lauryl ether and polysorbate 80.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
