Abstract
A 58-year-old man was referred to our hospital because of acute heart failure. He was diagnosed as hypertensive cardiomyopathy, and started treatment of heart failure and hypertension. After 6 months of combination therapy, we modified the treatment, and started telmisartan, then, follow-up examination of standard ECG-gated SPECT imaging was done. The SPECT data were reanalyzed by using new software, heart function view (Medi-Physics Co.), automatically. LVEF were used as markers of systolic function, and Peak phase, systolic phase standard deviation (Phase SD) and histogram bandwidth (Bandwidth) were used as markers of dyssynchrony. We also tested BNP concentration as a marker of heart failure. As shown in figure, telmisartan may have had favourable effects on heart failure in this case.Tabled 1TreatmentLVEF (%)EDV (ml)Peak Phase (°)Phase SD (°)Bandwidth (°)BNP (pg/ml)Pre-treatment (amlodipine 2.5mg)25.423114552.3181302amlodipine 2.5mgcarvedilol 2.5mg35.321112962.218334.3losartan 25mgperindopril 2mgamlodipine 2.5mg45.314113617.16813.6carvedilol 2.5mg50.211212917.16610telmisartan 40mg53.213913513.3494.8 Open table in a new tab
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