Abstract
Isolated synaptosomes of calf brain cortex lost 90% of their original Na + content and 70% of their K + content during 30 min incubation in Na +- and K +-free iso-osmotic medium. Electrical stimulation, and 5 mmol/l of taurine or GABA significantly reduced the outflow of Na + and K + ions during incubation, but 5 mmol/l of glutamate strongly increased their outflow. The effect of glutamate on ion outflow was slightly reduced by external electrical pulses.
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