Abstract
To evaluate effect of targeted individualized nutrition support on therapeutic effect and safety of patients with severe diseases during hospitalization. All patients were divided into control group and the observation group according to the time of admission. All enrolled patients received symptomatic treatment and intensive care. The control group received only basic nutrition support. There was no significant difference in NRS2002 score between the two groups at admission. Before intervention, there were no significant differences of total serum protein, serum albumin, hemoglobin content, liver and kidney functions and immune indexes between both groups. After intervention, the total serum protein, serum albumin and hemoglobin content of observation group was significantly higher than those of control group. The incidence of adverse events and complications of observation group was significantly lower than control group during hospitalization. The targeted individualized nutrition support could improve nutritional status of patients with severe surgical diseases during hospitalization.
Highlights
Patients underwent major surgery often show different degrees of organ failure or dysfunction due to the severity of the disease
It has been shown that the incidence of malnutrition in hospitalized patients in China is as high as 10%-60%, which is even higher for patients with severe diseases (Diab et al, 2017)
All patients were divided into the control group and the observation group according to the time of admission into ICU
Summary
Patients underwent major surgery often show different degrees of organ failure or dysfunction due to the severity of the disease. The nutritional status of patients with weak physical constitution is significantly worsened during hospitalization, which affects the therapeutic effect directly (Qian et al, 2017). The inadequate intake and utilization barriers of energy seriously impede the outcome and prognosis of the disease, it is critical to provide appropriate nutrition support to patients with severe diseases during active treatment (Wu et al, 2017). The nutrition support therapy has become an indispensable part of clinical support therapy for patients with severe diseases. Whether individualized nutrition support could reduce the severity of disease and improve the prognosis of patients with severe diseases was still unknown. This study is aimed at exploring the effect of individualized nutrition support on improving the therapeutic effect and safety of patients with severe diseases during hospitalization
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