Effect of TACE and radioactive 125I particles and Huaier granule in treatment of moderate and advanced liver cancer

Abstract

Objective To investigate the clinical effect of transcatheter arterial chemoembolization (TACE) and radioactive 125I particles and Huaier granule in the treatment of moderate and advanced liver cancer. Methods Eighty patients with moderate and advanced liver cancer were included and divided into 2 groups prospectively and randomly. The study group was treated with TACE and radioactive 125I particles and Huaier granule. The control group was treated with TACE and 125I particles implantation. Both groups were followed up for 12 months. The imaging evaluation of tumor lesions, improvement of clinical symptoms, AFP and liver function related indexes before and after treatment were determined to compare the short-term and the long-term effects between the two groups. Results The effective rates were 97.1%, 85.7% and 71.4% and 57.1% in the study group and the control group at half a year and 1 year after the operation, respectively. The effective rate in the study group was significantly higher than that in the control group (P<0.05) . The liver injury in the study group was lower than that in the control group. Conclusion TACE and radioactive 125I particles and Huaier granule in the treatment of moderate and advanced liver cancer is effective, safe and reliable. Key words: Liver neoplasms; Chemotherapy, cancer, regional perfusion; Brachytherapy; Huaier granule