Abstract
The effect of T-2 toxin (2.35mg/kg of feed) on lipid peroxidation and on the antioxidant defence system was studied in blood plasma, red blood cells (RBC), liver and spleen of broiler chickens. The influences of antioxidant vitamin E (10.5mg/animal/day)+selenium (0.045mg/animal/day) and toxin binder (yeast cell wall extract, 2mg/kg of feed) supplementations on pathophysiological changes associated with the consumption of T-2 toxin contaminated feed was also investigated. T-2 toxin did not enhance the lipid peroxidation processes but had effect on the ascorbic acid and glutathione redox system. The antioxidant and toxin binder supplementation beside T-2 toxin load has beneficial effect on the antioxidant status, primarily the activity of the glutathione peroxidase (GSH-Px).
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