Abstract

The success of endodontic surgery has been shown to depend partly on the apical seal. Grey mineral trioxide aggregate (GMTA) produces hydroxyapatite twice as often as white mineral trioxide aggregate (WMTA) when suspended in a phosphate buffered saline (PBS) solution. The aim of this in vitro study was to compare the microleakage phenomenon of gray and white mineral trioxide aggregates as root-end filling materials after immersion in synthetic tissue fluid (STF). 55 single-rooted extracted maxillary anterior human teeth were divided into two experimental groups of 20 teeth each, plus 3 groups of 5 teeth each as two negative and one positive control groups. The root canals were cleaned, shaped, and laterally compacted with gutta-percha. The root ends were resected and 3 mm deep cavities were prepared. The root-end preparations were filled with GMTA or WMTA in the experimental groups. Leakage was determined using a dye penetration method. Data were analysed using analysis of variance (ANOVA) at the 0.05 level of significance. The mean dye leakage was 0.40 ± 0.1 mm for GMTA and 0.50±0.1 mm for WMTA groups, respectively. There was no significant difference between the two experimental groups (P = 0.14). Despite the different properties and behaviours of GMTA and WMTA in STF, there were no significant differences in microleakage when using GMTA or WMTA.

Highlights

  • Effect of Synthetic Tissue Fluid on Microleakage of Grey and White Mineral Trioxide Aggregate as Root-End Filling Materials An in vitro study

  • Advances in Knowledge - Root-end filling materials play a crucial rule in the success of periapical surgery. - Using bioactive materials for root-end filling purposes has demonstrated promising treatment in periapical surgery to increase success rates, as shown in this study. - On the basis of available information, it appears that mineral trioxide aggregate (MTA) is the material of choice for periapical surgery

  • MTA has two versions: white and grey, and choosing one over the other to use as retrofill material is still under question. - This study will help in choosing an appropriate root-end filling material for patients needing periapical surgery

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Summary

Introduction

Effect of Synthetic Tissue Fluid on Microleakage of Grey and White Mineral Trioxide Aggregate as Root-End Filling Materials An in vitro study. - This study will help in choosing an appropriate root-end filling material for patients needing periapical surgery. Endodontic surgery may be indicated if conventional root canal therapy cannot treat complex anatomy, procedural misadventures, or inflammatory processes.[1,2] Root-end filling materials are used in periapical surgery to seal the root canal from the periapical tissues.[1] An ideal root-end filling material should be biocompatible and able to seal, insoluble in tissue fluids, non-resorbable, radiopaque, and dimensionally stable.[3] Increasing the sealing ability of materials can lead to more successful endodontic treatments.[3] Mineral trioxide aggregate (MTA) was first introduced in 1993 as a root repair material and is a mixture of Portland cement, gypsum, bismuth oxide, and trace amounts of metallic oxides.[4,5,6,7] The first generation of MTA was grey in colour. White MTA (WMTA) was introduced in 2002 as an alternative to grey MTA (GMTA) which does not match with the colour of the anterior teeth.[8]

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