Abstract
SummaryLong-term administration of synthetic salmon calcitonin to rabbits markedly decreases the radioiodine (131I) uptake in the thyroid gland as well as in the plasma. Protein-bound iodine and thyroxine serum levels are also decreased. In contrast, the renal iodine clearance is much increased in calcitonin-treated rabbits as compared to controls or to vehicle alone. This ioduric effect of salmon calcitonin can explain its role in goiter induction.This study was supported in part by NIH-General Grant, and Detroit General Research Corporation. We thank the Armour Pharmaceutical Company for the kind supply of synthetic salmon calcitonin used in this study.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
