Abstract

The present study was conducted to investigate the efficacy of supplementation of phyto-pharmaceutical producton the immune status of cows during transition period. Twelve crossbred cows in their late gestation were selected and randomly divided into two groups as control group (CON) and supplemented group (SG). The cows in the CON were fed as per the NRC standards while SG were supplemented additionally with 20g of poly-herbal formulation containing Boswellia serrata(Burseraceae) and 20g of Berginia ciliata (Saxifragaceae) for 21days prepartum to 7 days postpartum. Immune status viz., total leucocyte count (TLC), neutrophil percentage (%), lymphocytepercentage (%), neutrophil: lymphocyte ratio (N:L), in-vitrophagocytic activity (PA) of blood neutrophils, plasma cortisol level, interleukin-2 (IL-2) and interleukin-8 (IL-8) were estimated as well as effects were studied on milk for somatic cell count(SCC) and its constituents (fat, protein and lactose) too. Results showed that supplementation mixture significantly (P<0.05)reduced cortisol levels, IL-2, IL-8, TLC, neutrophil % and neutrophil: lymphocyte ratio whereas lymphocyte % increased.PA also increased significantly (P<0.05) on day of parturition. Milk SCC levels were higher (P<0.05) and milk lactose was lower(P<0.05) in the CON as compared to the SG. It was inferred that feeding of the phyto-pharmaceutical product effectively reduces stress and enhance immunity during transition period

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