Abstract
Objective: To evaluate the effect of supplementary administration of Anaheal capsule in reducing pain, swelling and trismus after surgical removal of impacted mandibular third molars. Material and Methods: This single-blind controlled randomized clinical trial was conducted on 36 patients referring to Tabriz University of Medical Sciences. Each of the 36 patients had bilateral surgical removal of mandibular third molars in two sessions, with at least a 4-week interval between sessions. In the same individual, one of the sites randomly received a test medication whereas the other site was used as a control. In the test subgroup (test medication side), the first dose of Anaheal capsule was given as a 200-mg dose of bromelain immediately after surgery according to manufacturer’s instructions and the subsequent doses were given at 6-hour intervals after the first dose. The medication was administrated for 3 days. In the control subgroup (control side), Anaheal was not administered. The severities of pain, swelling and maximum mouth opening (MMO) were recorded one and three days postoperatively. Paired t-test and t-test for independent samples were used. Statistical significance was defined at p 0.05). Conclusion: Supplementary administration of Anaheal (800 mg bromelain daily) had no significant effect on decreasing pain, swelling and trismus at 1- and 3-day intervals after surgical removal of mandibular third molars.
Highlights
Wisdom teeth remain impacted in the jaw for various reasons, including high density of overlying bone, the position of adjacent teeth, thick mucosa and genetic factors
In the test subgroup, the first dose of Anaheal capsule was given as a 200-mg dose of bromelain immediately after surgery according to manufacturer’s instructions and the subsequent doses were given at 6-hour intervals after the first dose
Pain, swelling and trismus of the patients were at the highest levels one day after surgery, which decreased on day 3
Summary
Wisdom teeth remain impacted in the jaw for various reasons, including high density of overlying bone, the position of adjacent teeth, thick mucosa and genetic factors. The prevalence of impacted mandibular wisdom teeth is 20-30% of the population; surgery of impacted wisdom teeth is one of the most frequent surgeries in dental field [1,2]. This type of surgery inflicts traumas to the highly vascularized region of the impaction, leading to inflammatory complications, referred to as 'sequelae', because they are common occurrences and include pain, swelling and trismus [3]. Pain, swelling and trismus are frequent complications after impacted third molar surgeries. These complications affect the quality of life [4]. An important principle in dentistry is to reduce the incidence of postoperative complications [5,6]
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