Effect of superovulation on maternal serum progesterone concentration, uterine and fetal weights at weeks 7 and 15 of pregnancy in Javanese Thin-Tail ewes

Abstract

Twenty-one pregnant ewe lambs (nine superovulated and 12 non-superovulated) were used to study the effects of superovulation (injecting 700 IU PMSG at the end of diestrus) on maternal serum progesterone concentrations, uterine and fetal weights at weeks 7 and 15 of pregnancy. In the ewes sacrificed at week 7 of pregnancy, superovulation increased the mean number of corpora lutea ( P<0.01), fetuses ( P<0.01), maternal mean serum progesterone concentration ( P<0.01), mean uterine weight ( P<0.05), total fetal weight ( P<0.01), and average fetal weight ( P<0.01) by 133%, 69%, 354%, 66%, 150% and 40%, respectively, when compared to non-superovulated ewes. In the ewes sacrificed at week 15 of pregnancy, superovulation increased the number of corpora lutea ( P<0.01), fetuses ( P<0.05), maternal serum progesterone concentration ( P<0.01), uterine weight ( P<0.05), total fetal weight ( P>0.05), and average fetal weight ( P<0.05) by 207%, 20%, 84%, 37%, 29% and 24%, respectively, compared to those non-superovulated ewes. It was concluded that the increased number of corpora lutea and, therefore, their hormonal secretions by superovulation could increase uterine and fetal growth and development.