Effect of sulfonamide cream on the bacterial flora of the infected vagina and cervix

Abstract

1.1. The incidence of bacteria found in the vaginal and cervical secretions of patients with “nonspecific leucorrhea,” excluding those with trichomonas, monilia, or gonorrheal infection, is presented. Twenty-seven microorganisms were isolated, of which the most frequent were staphylococcus albus; alpha, beta, and gamma streptococci, diphtheroids, and colon bacilli. The variety of organisms isolated in any single patient varied from three to twelve, with an average of seven. Anaerobic streptococci were relatively rare.2.2. A multiple sulfonamide cream is effective in suppressing the coccal organisms and ineffectual in eradicating diphtheroids and coliform species from vaginal and cervical secretions. When used in ten patients after cauterization, it gave striking diminution in postcautery discharge and bleeding. In thirty-five other patients, fifteen noted relief of discharge following three weeks of daily therapy with the cream alone. No improvement of the cervical erosions could be demonstrated within this period.