Abstract
Abstract: Feeding high sucrose diets to human volunteers and experimental animals results in impaired glucose tolerance, hyperlipidemia and impaired serum insulin‐like activity. Breeding selected rats with impaired glucose tolerance caused by sucrose feeding produces in succeeding generations: diabetes, renal arteriosclerosis, and renal and retinal diabetic‐like angiopathy. The starch‐fed siblings develop none of these changes. The interaction between genetics and sucrose consumption in the production of diabetes mellitus is thus proved.This experimental model explains the development of diabetes in Yemenite Jews immigrating to Israel. In the Yemen, where their diet contained no sucrose, the incidence of diabetes was extremely low. After settling in Israel, where they consumed large amounts of sucrose, the incidence of diabetes has risen.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
