Abstract
ABSTRACTGlass surfaces with well defined surface morphologies have been prepared using photolithography to study the effect of surface morphology on cell adhesion and function. Using a transformed recombinant cell-line, AtT-20, as a model of shear sensitive cell, we have shown that cell-substratum adhesion strength is enhanced using a surface with uniform grooves without any loss in cellular function. Furthermore, using primary hepatocytes as a model for a cell whose function is sensitive to its shape, we have shown that surface morphology can modulate cell shape as well as its function.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
