Abstract
Serum iron (SI), total iron binding capacity (TIBC), and serum bilirubin levels have been used as diagnostic criteria in man for early clinical stages of various types of anemia. For example, Carr reported that when the ratio of SI to TIBC was less than 16%, a state of iron deficiency hernia exists whereas mean corpuscular hemoglobin (MCH) and mean corpuscular volume (MCV) may still be within the normal range (1). In 1971, Bloomer et at. (2) showed that in congenital nonhemolytic jaundice the serum bilirubin concentration is about 40 times normal. A similar level of serum bilirubin was observed by Keaster et at. (3) in hemolytic disease of the newborn. Jaffe and Bishop (4) reported decreased serum iron during clinical stages of Hodgkin's disease. Hargrove (5) showed a marked increase in serum bilirubin in sickle
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More From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
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