Effect of Storage Period on Platelet Count and Erythrocyte Morphology in Whole Blood Bags

Abstract

Platelets and erythrocytes undergo transformation during storage, which may cause them to become inactive or non-functional. In transfusion medicine, the storage period of platelets and erythrocytes is very important because they change shape during storage, such as during echinocytosis, spherocytosis, and crenation. This study aims to determine the effect of storage period on platelet count and erythrocyte morphology in whole blood samples. Methods: This study used simple random sampling method to determine the effect of time on the occurrence of a disease. The study was conducted from January to April 2022 at the Semarang Regency Blood Donor Unit. This study focuses on the effect of time on the occurrence of a disease in whole blood samples. This study used automated sampling with hematology analyzer to analyze the data. Data collection was done with informed consent from donors and laboratory data from Blood Donor Unit Semarang Regency. The results showed a significant difference in changes in platelet count and erythrocyte morphology between day 0 and day 30 storage periods, with a p value of 0.014. Conclusions. There is a significant difference in changes in platelet count and erythrocyte morphology between day 0 and day 30 storage periods with a p value of 0.014. It is recommended that in the process of storing blood bags in the Blood Donor Unit, excessive shelf life is avoided to maintain blood quality.