Abstract

Improving the reproductive performance of cattle is one of the main tasks in livestock. Numerous stressors, high productivity, poor feeding, improper conditions of care and operation cause hormonal changes in the system "hypothalamus-pituitary-ovaries" of females, which negatively affects reproduction. As a result, farms do not receive a certain amount of offspring and milk, and in the future - an increase in the infertility rate of uterine cattle. In cows after calving at the initial stage of lactation, the trophic function of the pituitary gland is more aimed at ensuring the secretion of milk than at restoring the cyclic activity of the ovaries. Therefore, to correct the reproductive capacity of cows use: feed additives, hormonal drugs, trace elements, physiotherapy methods and more. There are a small number of studies on the effects of biologically active drugs with neurohumoral action on the reproductive function of cows. The aim of our research was to establish the effects of biologically active substances of the neurotropic-metabolic drug "Stimulin-Cattle" on the reproductive capacity of cows. The studies were conducted on the basis of groups of analogues. The experiment selected cows after the first insemination and females who came back to sexual hunting. Experimental animals on day 7 - 9 of the sexual cycle were injected subcutaneously in the scapular region with 20 ml of the drug "Stimulin-Vet", and control according to the same scheme saline sodium chloride solution 0.9%. Cows were inseminated once by recto-cervical method. Three months later, rectal examinations of the animals were performed to determine pregnancy. The analysis of the obtained results showed that in experimental cows the fertility exceeded the control by 15.4 %. In the experimental group, 56.4 % came to sexual hunting again, and in the control group 71.8 %. Among 22 non-pregnant experimental cows, the cause of infertility in 63.6 % of animals was the anovulatory cycle, and in 36.4 % embryonic mortality. Whereas in the control of animals with anovulatory cycle was less by 42.2 %, and with embryonic mortality by the same percentage is probably higher. This situation with infertile animals suggests that the drug stimulates the development of the corpus luteum on the ovary, which promotes the secretion of more progesterone, which causes better conditions for embryo engraftment and thus reduces embryonic mortality. It was also found that animals after the first insemination react worse to the introduction of the drug than those who were inseminated for the first time, which confirms the level of fertility of 41.7 % vs. 46.7 %, respectively.

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