Abstract
Effect of steroid-free follicular fluid antiserum on reproductive endocrine profile at estrous and metestrus phases in female rats
Highlights
The endocrine systems play a main role in the estrous cycle
In comparison between the two phases, S-FBFF-ab treated group females recorded significant (P0.05) difference between the two phases (Table 1)
In comparison between the two phases, S-FBFF-ab treated females recorded significant (P0.05) difference between the two phases (Table 2)
Summary
The endocrine systems play a main role in the estrous cycle. Various hormones involved are gonadotrophins (LH and FSH), estrogen and progesterone [1]. FSH promotes folliculogenesis, while LH triggers ovulation in the ovary and develops corpus luteum [2]. During the development of follicles, the level of estradiol is increased. The rise in estradiol level stimulates the part of adenohypophysis, the combination of effects on the hypothalamus and adenohypophysis will triggers the ovulatory surge of LH [3]. Researchers have other choices to be induce superovulation, other than eCG-hCG treatment, in order to solve this problem in rats and immunizing against inhibin as in other animals. Multiple discoveries have proven that immunization against inhibins stimulates superovulation in both immature and adult rats [4,5,6,7,8,9,10]
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