Abstract
The interaction of static magnetic field (SMF) with living organisms is a rapidly growing field of investigation. Recently, exposure to moderate intensity SMFs (1 mT – 1 T) has attracted much attention for its various medical applications. This study was designed to show the microscopic effect of SMF on erythrocytes in vitro. For this purpose SMF system was constructed in my lab on basis of the idea of cell tracking velocimetry system. The changes in erythrocytes surface area, sphericity, and adhesion number for erythrocytes were calculated to quantify the effect of SMF on erythrocytes characterizations. The results showed that SMF increased erythrocytes surface area and reduced their sphericity. The adhesion number of erythrocytes under the influence of SMF showed the tendency of erythrocytes to adhere with each other. These findings indicate that more study on microscopic scales must be carried out in order to investigate the effect of SMF on erythrocytes.
Highlights
During the last few years there has been an increasing interest in the influence of magnetic field on biological cell [1]
The results showed that static magnetic field (SMF) increased erythrocytes surface area and reduced their sphericity
The adhesion number of erythrocytes under the influence of SMF showed the tendency of erythrocytes to adhere with each other. These findings indicate that more study on microscopic scales must be carried out in order to investigate the effect of SMF on erythrocytes
Summary
During the last few years there has been an increasing interest in the influence of magnetic field on biological cell [1]. Reports from in vitro research indicate that low level high frequency fields may alter membrane structural and functional properties that trigger cellular responses. Since water is the main component of biological systems and all metabolic processes take place in aqueous medium it was supposed that even minor changes in the physico-chemical properties of water could significant modify cell functional activity. Erythrocytes are often used as model in exploring the structure and function of the biological cells as well as studying the effect of different physical and chemical factors on the cell.
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