Abstract
The basal secretion of the pancreas and the secretion stimulated by duodenal perfusion were investigated in chronic experiments on dogs. A protein digest stimulated pancreatic enzyme secretion to a greater degree than protein itself. Amobarbital, chlorpromazine, and benactyzine inhibit both basal and stimulated pancreatic secretion. The differential character of pancreatic secretion was disturbed most by chlorpromazine and benactyzine; this is evidence of the essential role of central adrenergic and cholinergic structures in the adaptation of pancreatic secretion to food stimuli.
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