Effect of some hormones on calcium balance in elderly subjects.

Abstract

Our earlier studies on calcium and phosphorus balance in elderly subjects have shown that calcium requirements are higher for such subjects than other workers found for young adults, with little change in phosphorus requirements (1,2). We later noted that addition of Vit. D to a supposedly adequate diet increased calcium retention in these subjects (3). Increased calcium requirements in the aged make it more likely that such subjects will be in negative calcium balance on an ordinary diet. The increase in incidence of osteoporosis in the aged has been noted by many workers(4). We have been studying the effects of various hormones on nitrogen balance in elderly subjects for some time. Some cause an increase in nitrogen retention and definite clinical improvement(5,6). Use of these hormones has found a definite place in treatment of debilitated elderly subjects(7). In view of the precarious state of calcium equilibrium in such individuals, we felt it advisable to make further studies on the effect of these ...