Abstract
The histological changes in the corpuscles of Stannius (CS) and the thyroid gland were studied after administration of two antithyroid drugs, viz., thiourea and thiouracil in the catfish, Heteropneustes fossilis (Bloch). Injections of thiourea resulted in hypertrophy, hyperplasia, and hyperaemia of the thyroid follicles, whereas thiouracil treatment produced stimulatory changes in the thyroid gland up to 30 days only. After a prolonged immersion in thiourea solution the hypertrophied thyroid follicles underwent atrophic changes. Despite pronounced alterations in the thyroidal activity no significant changes could be discerned either in the granularity or in the cell and nuclear diameters of the CS. It, therefore, seems that a lack of thyroid hormone has no apparent effect on the CS of the catfish.
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