Abstract

The zeta potential of oxytetracycline hydrochloride stabilized emulsion flocculated by the addition of anionic surfactants has been calculated. The interaction energies of these emulsions have also been evaluated and the stability discussed in the light of D. L. V. O. Theory. The energy barriers, thus obtained, were very high, which prevented the occurrence of flocculation in primary minima. The flocculation could, however, occur in the secondary minima. The flocculation studies were carried out haemocytometrically and the degree of aggregation (D) calculated. In order to account for the observed values ofD, the effective Van der Waals constant of the system should be 2.3 x 10-13 erg. The binding parameters and free energy of adsorption have also been calculated.

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