Abstract

Introduction: The aim of this study was to assess the induction of solvents on the total phenol and flavonoid content and also the antioxidant activity of Ganoderma lucidum extracts. Materials & Methods: In this study, two concentrations (100% and 75%) of diethyl ether, ethanol, butanol, chloroform, and acetone were used as extractants of Ganoderma lucidum. Total phenol and flavonoid contents were measured by spectrophotometric methods and 1, 1-diphenyl-2-picrylhydrazyl (DPPH). Free radical scavenging assay was used for the investigation of antioxidant activity. Results & Discussion: Extractants significantly affected the % yield of extract, the quantity of phenol and flavonoids and antioxidant activity of Ganoderma lucidum mushroom. The highest extraction yield, around 38%, was achieved by 75% acetone, followed by 100% acetone (about 36%) and 75% chloroform (approximate 21%). Hydro-acetone extract exhibited the most significant antioxidative properties (EC50 value; 645.55 µg/mL) comprised of a higher total of phenol content. In conclusion, the total phenol content encouraged the antioxidative potential of Ganoderma lucidum mushroom. Conclusion: These findings indicate that the selective extraction of Ganoderma lucidum shows significant biological activities.

Highlights

  • The aim of this study was to assess the induction of solvents on the total phenol and flavonoid content and the antioxidant activity of Ganoderma lucidum extracts

  • The total phenol content encouraged the antioxidative potential of Ganoderma lucidum mushroom

  • These findings indicate that the selective extraction of Ganoderma lucidum shows significant biological activities

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Summary

Introduction

The aim of this study was to assess the induction of solvents on the total phenol and flavonoid content and the antioxidant activity of Ganoderma lucidum extracts. Pleurotus ostreatus, Ganoderma lucidum, and Lentinula edodes are available in Bangladesh and comprise different phytochemicals such as polyphenols, flavonoids, tannins, steroids [4]. Suphaphit Boonsong et al have shown that different extractants induced antioxidant potential of edible mushrooms [6]. In 2002, Yang et al from China have demonstrated that tree oyster mushrooms were signal properties of free radical scavenging abilities and comprised the highest content of total phenol [7]. The free radical scavenging activity of Ganoderma lucidum was encouraged by the presence of total phenol content [8]. It is known that Ganoderma lucidum comprises potential phytoconstituents which are concomitant with the advancement of good health as well as used for alternative medicine [9]

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