Abstract
Abstract The solubilisation of hexachlorophane by various non-ionic agents has been studied at pH 2·5 and 8·0. The interaction of the phenol with these agents in unsaturated systems at pH 8·0 has been determined by a dialysis technique using rubber latex membranes. The bactericidal activity is shown to depend on the concentration of unbound hexachlorophane, but this is not simply related to the degree of saturation of the total system. The results of agar-plate diffusion tests cannot be correlated with either the concentration of unbound hexachlorophane or the total concentration.
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