Effect of Smear Layer on Penetration Depth of Methylene Blue and Curcumin into Root Dentinal Tubules

S Toursavadkouhi,R Ghaseminejad,A Azizi,M Fazlyab

doi:10.52547/jrdms.6.4.8

Abstract

Effect of Smear Layer on Penetration Depth of Methylene Blue and Curcumin into Root Dentinal Tubules

Highlights

There has been a growing interest in use of photodynamic therapy (PDT) as an adjunct for treatment of endodontic infections
It has been shown that methylene blue and curcumin are effective photosensitizing agents for inactivation of endodontic bacteria.[3,4,5]Curcumin is a natural photosensitizer, which is extracted from the Curcuma longa
ANOVA showed a significant difference among the experimental groups in terms of photosensitizer penetration depth into dentinal tubules (P=0.001)

Summary

Introduction

There has been a growing interest in use of photodynamic therapy (PDT) as an adjunct for treatment of endodontic infections. PDT requires a light source to activate a non-toxic photosensitizing agent to create singlet oxygen and free radicals, which can induce the death of microorganisms. This study assessed the penetration depth of methylene blue and curcumin in presence/absence of smear layer into dentinal tubules. ANOVA was used to assess the effect of photosensitizer type, smear layer, and root level on penetration depth. Smear layer removal from the apical and middle thirds was correlated with higher photosensitizer penetration depth (P=0.000) but this difference was not significant in the coronal third (P=0.6). Curcumin had significantly greater penetration depth in presence of smear layer in all three parts compared with methylene blue (P

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Conclusion