Abstract
(1) Cells ofSerratia marcescens which survive repeated irradiation with X-rays are capable, after a further single dose of irradiation, of forming a higher percentage of variants. The percentage of variants increases almost linearly in relation to the dose. (2) A deviation from this linear course occurs in the small dose range (34 r. to 160 r.). The percentage of mutations suddenly increases and the differences as compared with the initial value are statistically significant. This is followed by a decrease in the mutation percentage, in agreement with the linear relationship to the dose found in earlier experiments. (3) Apart from previous irradiation, the sensitivity of clones ofSerratia marcescens is also determined by the initial mutation percentage. The longer the interval after cumulative irradiation, the lower this percentage.
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