Abstract
to analyze the effect of vertical gastrectomy on lipid profile and cardiometabolic risk in young women, preoperatively and 6 months after the operation. retrospective study, encompassing medical record reviews of women's charts, preoperatively and in six months after the operation. Data collection was performed in the second half of 2015, using a review protocol with questions on the clinical-laboratory profile, anthropometric and laboratory classification of dyslipidemias. Descriptive and inferential analysis were used to treat the variables, using measures of variance, association and linear regression. we analyzed medical records of 114 women undergoing vertical gastrectomy, with a mean age of 33.82±10.92, and with complete high school education. There was a significant reduction of anthropometric data, as well as serum lipid values, six months after the surgical procedure. The coefficients of determination and the results of linear regression, showed that the reduction in serum triglyceride values and increase in high-density lipoprotein have a direct impact on the reduction of the cardiometabolic risk. Regarding the laboratory classification of dyslipidemias, it was observed that the majority presented a significant reduction at the six-month follow-up. Mixed hyperlipidemia showed no significant reduction. The categorized cardiometabolic risk showed a significant reduction in women at risk before vertical gastrectomy. at the six-month follow-up, vertical gastrectomy was effective in reducing the serum lipid profile and the cardiometabolic risk of young women when compared to the preoperative data. There was also a different improvement in the laboratory classification of dyslipidemias at the six-month follow-up after the surgical procedure.
Highlights
AObesity is a global public health problem, with increasing prevalence in developed and developing countries
Dietary restriction of sugars and fat, as well as the practice of regular physical activity, are essential to reduce the risks of comorbidities
Studies have shown that sleeve gastrectomy has influence in the reduction of low density lipoproteins (LDL-c), total cholesterol (TC ), triglycerides (TG), and in the increase in high density lipoprotein (HDL-c)[11,12,13]. These results show clinical improvement in chronic diseases, such as arterial hypertension and Diabetes Mellitus
Summary
AObesity is a global public health problem, with increasing prevalence in developed and developing countries. The World Health Organization (WHO) points out that more than 700 million people have morbid obesity, conditioned by eating habits, such as increased consumption of saturated fats and simple sugars, and decreased consumption of vegetables, grains and fruits. Psychosocial factors, political, economic and cultural issues, associated with the inadequacy regarding food intake, favor body weight gain, being a condition that requires decentralized interventions for its reduction[1]. The obesity associated with abnormalities in lipids’ metabolism, glucose, and blood pressure, increases the probability of risk for cardiovascular diseases such as cerebrovascular events and Acute Myocardial Infarction[3,4]. Dietary restriction of sugars and fat, as well as the practice of regular physical activity, are essential to reduce the risks of comorbidities. A methanalysis encompassing six interventional studies did not indicate food and energy restriction as effective in weight loss[5]
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