Abstract
Paid volunteers, 18 male college students, were deprived of sleep for one night on two separate occasions when alone. On a third occasion they were asked to stay up all night in groups of four. Plasma concentrations of 17-hydroxycorticosteroids at 8:00 a.m. following the nights without sleep were 4–5 μg lower than control values (significant at .01 level). The noon values after sleep deprivation in a solitary setting were not significantly different from the corresponding control values. When subjects stayed up with three other people, the noon values tended to be higher. Urinary 17-hydroxycorticosteroid levels showed a decrease following the nights without sleep, but this decrease did not reach statistical significance (between the .10–.05 level). Submitted on May 21, 1959
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