Abstract
It is important for elderly people to maintain or improve muscle strength and for clinicians to know the factors that affect muscle strength. Therefore, the purpose of this study was to compare the effects of fat mass (FM) and skeletal muscle mass (SMM) on muscle strength. The participants included 192 community-dwelling elderly women. The SMM and FM, grip strength, and knee extension strength were measured. Data were evaluated using stepwise multiple linear regression analysis, which was performed with grip or knee extension strength as a dependent variable and the SMM and FM of the upper and lower limbs as the independent variables. The SMM and FM of the upper limbs were associated with grip strength, whereas the SMM but not the FM of the lower limbs was associated with knee extension strength. These findings suggest that there may be thresholds for the SMM/FM ratio to affect muscle strength.
Highlights
Muscle strength decreases with aging [1], and this decrease is characterized by a slow walking speed [2], which in turn is associated with mortality [3]
The analysis showed that the skeletal muscle mass (SMM) and fat mass (FM)
Our findings suggest that intramuscular adipose tissue increases as FM increases
Summary
Muscle strength decreases with aging [1], and this decrease is characterized by a slow walking speed [2], which in turn is associated with mortality [3]. It is well known that skeletal muscle mass (SMM) is associated with muscle strength [5]. Fat mass (FM), which is higher in the elderly than in younger individuals [6], has been shown to affect muscle strength negatively. Intramuscular adipose tissue inhibits central activation, resulting in a reduction in muscle strength [7]. It produces tumor necrosis factor (TNF-α) [8], which reduces muscle performance [9]. We hypothesized that SMM and FM affects muscle strength among the elderly.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
