Abstract
The purpose of this study is to investigate the effect of six weeks of HIIT under simulated microgravity conditions on morphological changes of radial nerve myelin sheath in male rats. In the present study, 24 male wistar rats were randomly selected and divided into four groups including: TS (training during suspension: n=6), CS (suspension: n=6), T (training: n=6), C (control: n=6). The training groups run on treadmill for six weeks (five days a week). 24 hours after the last training session, animals were prepared for tissue samples. At the end of the experiment, changes in myelin sheath were measured by Luxol fast blue. obtaining results showed that the percentage of changes in myelin sheath in HIIT group under simulated microgravity (p≤0.001) was higher than other groups, significantly (30/27+5/27). Based on the results, HIIT under simulated microgravity conditions affected on changes in myelin sheath. Therefore, it can play an effective role in the improvement of clinical status of neurological patients and decrease side effects in Astronauts.
Highlights
The purpose of this study is to investigate the effect of six weeks of HIIT under simulated microgravity conditions on morphological changes of radial nerve myelin sheath in male rats
At the end of the experiment, changes in myelin sheath were measured by Luxol fast blue. obtaining results showed that the percentage of changes in myelin sheath in HIIT group under simulated microgravity (p≤0.001) was higher than other groups, significantly (30/27+5/27)
HIIT under simulated microgravity conditions affected on changes in myelin sheath
Summary
The purpose of this study is to investigate the effect of six weeks of HIIT under simulated microgravity conditions on morphological changes of radial nerve myelin sheath in male rats. هدف از پژوهش حاضر بررسي تأثير شش هفته تمرين تناوبي شديد تحت شرايط ميكروگراويتي بر تغييرات ساختاري غلاف ميلين عصب راديال موشهاي صحرايي نر است.
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