Effect of Single Nostril Transsphenoidal Resection of Pituitary Adenoma under Neuroendoscope on Hospitalization Time and Bleeding Volume in Patients with Pituitary Adenoma

Abstract

Objective: This study mainly discusses the clinical effect of treating pituitary adenoma by using single nostril transsphenoidal resection of pituitary adenoma under neuro-endoscope, and analyzes the influence on hospitalization time and bleeding volume. Methods: A total of 335 patients with pituitary adenoma treated in our hospital from January 2017 to January 2019 were randomly selected for study. The patients were divided into two groups by number table method. 167 patients in the reference group underwent single nostril transsphenoidal resection of pituitary adenoma under microscope. Also, 168 patients in the study group underwent single nostril transsphenoidal resection of pituitary adenoma under neuroendoscope. The hospitalization time and bleeding volume and other surgical treatment effects were observed and compared. Results: There was no significant difference in the levels of prolactin (PRL), adrenocorticotropic hormone (ACTH) and thyroid stimulating hormone (TSH) between the two groups before operation (P > 0.05); After surgical treatment, the levels of PRL, ACTH and TSH in the study group were lower than those in the control group (P < 0.05); In terms of surgical indexes, the operation time and hospital stay in the study group were shorter than those in the reference group, and the amount of surgical bleeding was less than that in the reference group (P < 0.05); The total tumor resection rate in the study group was higher than that in the reference group, and the incidence of complications such as nasal septal defect, cerebrospinal fluid leakage and diabetes insipidus in the study group was lower than that in the reference group (P < 0.05). Conclusion: For pituitary adenoma diseases, using single nostril transsphenoidal resection of pituitary adenoma under neuroendoscope can improve the tumor resection rate, reduce the bleeding volume and shorten postoperative hospitalization time.